MrIncredible
Is fintastic
It depends on what you are aiming for. If you want just a regular job that pays 50 Gs a year, then don't bother with customization, nor does it matter if your resume is one page or two, just make sure everything sounds ok and is spelled correctly.
Personally, I custom tailor my resume for any job application since I'm at that point in my career where if it's a job I'd even consider taking, I'm probably coming in via referral and the employer will probably be closely scrutinizing my experience. But I also keep it to one page, and I focus only on accomplishments, not responsibilities.
I throw away any applicant who doesn't lay things our clearly and with proper spelling. If your best work isn't right I can't be bothered with you.
Don't trust the spell checker either! If you have the decidedly wrong word someplace it's more of the same dumbfuckery that is so prevalent.