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An experimental treatment completely reversed Alzheimer’s disease in mice by reducing the levels of a single enzyme in the animals' brains. Scientists at the Cleveland Clinic theorized that reducing BACE1 in the brain would have a trickle-down effect, reducing plaque formation. In their...

Citing “systematic manipulation” of anti-doping rules, a 14-person International Olympic Committee panel announced Tuesday it has banned Russia from the 2018 Winter Olympics in PyeongChang. As a result of this ban, no Russian officials will be allowed to attend the games. Their flag will be...

** ANNUAL CHRISTMAS GATHERING!! ** Wednesday December 20, 2017 What - A fun event where you can meet BARFers, eat drink & be merry, and exchange some cool gifts! And probably some really oddball ones too!! Where - Skipolini's Pizza, 2001 Salvio St, Concord, CA (925) 680-6888 When - Wednesday...

My Road King has a bit of rust on the head bolts. In a perfect world I would simply pull one out and replace it with a new one, torqued to proper spec without loosening and tightening the others in their proper sequence. Real-world scenario, how bad of an idea is this?

Probably more of an item for your work than your home. We use them to hold assembly parts together during transport, but can only use galvanized so these need to go away. 1,000 pieces @ 20" 2,000 pieces @ 32" Free to good home, located in Concord.

He died doing what he loved? Dipped past two lines of security and jumped the fuck into the burning structure. Better than fading away, I suppose.

Looks like one of them fell while being detained. :laughing "...At that time, the person who had been behind the counter knew that there was a retirement party for a police officer happening, so they went into the other portion and alerted the officers to the fact that they had just been...

Anyone watch this? SIWbjgPYcJY Amazing footage in this series. They make cameras that resemble the animals they're filming to get extremely close for extended lengths of time. aFjWQEhdMwE

A buddy that lives up there just got turned around by police at Bottlerock and 29.

BROUGHT TO YOU BY DAVENTURA.... CALLING ALL OG's TIME: 7 pm NOOBS WELCOME. Free moto parking out front. Wednesday is trivia night and it's srs business. Come one, come all. We'll dominate Trivia and earn free beer money in addition to shooting the breeze and talking motos. Pig and...

Enjoy your day, you glorious bastard.

CHP Incident page 7:51 AM 9 [26] 6 VEHS STOPPED, 3 VEHS ARE BLKG #2 LN [Shared] 7:51 AM 8 [25] WIT ADVD VEHS ARE STOPPED AROUND THE RIDER AND DRIVERS ARE OO THEIR VEHS [Shared] 7:47 AM 7 [15] SEVERAL PTYS OO VEHS STANDING IN LNS OF TRAFFIC [Shared] 7:47 AM 6 [10] SD IN CD [Shared] 7:47 AM 5...

Come on down to Skippolini's Pizza in Concord tonight and join us celebrating the life of a champion motorcyclist. Bring your #69 shwag to display, wear your favorite T-shirt from the USGP, or just show up to raise a glass to a racer taken much too soon. Skippolini's Pizza 2001 Salvio St...

How much of a hassle is it going to be at the DMV if the VIN has been somewhat covered up? Frame was powder coated and the VIN is there, but faint. The bike is fully assembled so it's difficult to see without a strong light, but the numbers are there. Will it be a matter of lucking into a worker...

A Minnesota man is accused of driving off and leaving his mortally injured girlfriend on the side of the road after she fell from his motorcycle. According to the complaint, officers could “smell an odor of alcohol on him, his speech was slurred, his pupils were constricted, he had a burnt lip...

:Party Happy birthday to one of the smarter cats I know.

Twerking woman causes major accident "...He turns his head toward the gyrating woman and in doing so, fails to notice an oncoming BMW. As a result, the motorcycle smashes straight into the car, catapulting the rider into the air..."

Good morning officers. How accurate are the radar readouts on the trailers that get parked in different locations? I've always used them (and the speed limit signs with radar) to somewhat calibrate my speedometers. However, a friend recently scoffed at me, saying he believed that they were set...

Carls Jr to Ditch Bikini Ads A new commercial for the chains shows the imagined Carl Hardee Sr. taking back control of the operation from immature son Carl Hardee Jr. Carl Sr. rips down photos of swimsuit models and puts up framed pictures of hamburgers.

Moto Forza in Escondido “Just watching all of these beautiful bikes just go up in flames watching tanks pop, it’s devastating," said witness Emily Bradsher, who said she could see the heavy smoke and flames from the freeway. “I noticed the flames were at least 100, 120 feet over the roof."...